WebSponsor Protocol Number: INCB 59872-103. About this study. The purpose of this study is to evaluate the safety and preliminary anti-tumor activity of INCB059872 in participants with Ewing sarcoma who are refractory or relapsed from prior standard therapy and not eligible for further standard systemic therapy. WebAn Open-Label Phase 1b Study of the Safety, Tolerability, and Preliminary Antitumor Activity of INCB059872 in Participants With Relapsed or Refractory Ewing Sarcoma
An Open-Label Phase 1b Study of the Safety, Tolerability, and ...
WebDrugs INCB 59872 (Primary) Indications Sickle cell anaemia Focus Adverse reactions; Pharmacodynamics Sponsors Incyte Corporation Most Recent Events 24 Oct 2024 Status … WebDec 4, 2024 · Histone demethylase LSD1 plays key roles during carcinogenesis, targeting LSD1 is becoming an emerging option for the treatment of cancers. Numerous LSD1 … pile mountain 違い
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WebSep 18, 2024 · Nonetheless, there is renewed interest in therapeutic targeting of LSD1 as several new compounds that disrupt LSD1 function including: GSK2879552, ORY-100, 4SC-202, IMG-7289, INCB-59872, and ... WebDec 20, 2024 · An Open-Label, Dose-Escalation /Dose-Expansion Safety Study of INCB059872 in Subjects With Advanced Malignancies Status: Active Age: 18 years and over Gender: Male or Female Location: 11 locations Primary ID INCB 59872-101 Secondary IDs NCI-2016-00447 Clinicaltrials.gov ID NCT02712905 BREAST CANCER WebINCB059872, also known as INCB59872, is a potent, selective, and orally active lysine-specific demethylase 1 inhibitor. INCB059872 binds to and inhibits LSD1, a demethylase … gtin jan itf