Hif-2 alpha
WebOur HIF-2 alpha monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell treatment and Knockdown to confirm specificity to HIF-2 alpha. Find the HIF-2 alpha antibody that fits your needs. Choose from 1 of 31 HIF-2 alpha antibodies, which have been validated in ... WebMA1-516 detects hypoxia-inducible factor 1 alpha (HIF-1 alpha) from human, non-human primate, bovine, mouse and porcine cells. This antibody does not cross-react with ARNT or the related HIF-2 alpha. MA1-516 has been successfully used in Western blot, immunofluorescence, immunoprecipitation, immunocytochemistry, ...
Hif-2 alpha
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WebHIF-2 alpha Antibody Staining Protocol for Immunohistochemistry . Description: HIF-2 alpha is also designated EPAS1 whose gene is mapped to 2p21-p16. The predicted mouse … WebThe HIF-2α inhibitor PT-2385 and CD70 inhibitor BU69 were used to specifically suppress these pathways. Stimulation with IL-17 and TNF-α significantly induced CD70 expression in RA FLS. Although the synovial fluids from patients with RA contained high levels of sCD27, surface expression of CD27, a ligand of CD70, was rarely detected in …
WebNational Center for Biotechnology Information http://www.ihcworld.com/products/antibody-datasheets/HIF2a.IW-PA1129.htm
Web在低氧状态下，hifα被保护免于降解，与hifβ及低氧调节基因中的特定dna 序列（hre）结合来激活下游基因的表达。hif-2α活性异常是透明细胞肾细胞癌（ccrcc）等癌症的关键致癌 … WebHIF-2-alpha was immunoprecipitated from 0.35 mg HeLa (Human cervix adenocarcinoma epithelial cell) cell treated with 1mM DFO for 24h, cell lysate 10 µg with ab207607 at 1/30 dilution (2µg in 0.35mg lysates). Western blot was performed on the immunoprecipitate using ab207607 at 1/1000 dilution.
WebHypoxia inducible factor (HIF)-1 and HIF-2 are heterodimeric transcription factors mediating the cellular response to hypoxia. Recent data indicate that not only ubiquitous HIF-1 …
Web25 de mar. de 2024 · In pathological cardiac hypertrophy, the heart is more dependent on glucose than fatty acids. This shift in energy metabolism occurs due to several factors, including the oxygen deficit, which activates hypoxia-inducible factor-1α (HIF-1α), a critical molecule related to glucose metabolism. However, … phone cases that work with razer kishiWeb15 de jun. de 2006 · Abstract. Overexpression of hypoxia-inducible factors (HIF), HIF-1alpha and HIF-2alpha, leads to the up-regulation of genes involved in proliferation, … how do you make a chocolate cake from scratchWebHypoxia-inducible factor. Hypoxia-inducible factors ( HIFs) are transcription factors that respond to decreases in available oxygen in the cellular environment, or hypoxia. [1] [2] … how do you make a circle in small basicWeb13 de jul. de 2024 · Patients receive HIF-2 alpha inhibitor PT2385 orally (PO) twice daily (BID) on days 1-28. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity. After completion of study treatment, patients are followed up every 2 months for 2 years and every 6 months thereafter. phone cases that charge your iphoneWebHIF-2 alpha is predominantly expressed in highly vascularized tissues of adult humans and endothelial cells of the embryonic and adult mouse, whereas HIF-1alpha functions primarily in extravascular tissues. HIF-2 alpha is also a potent activator of the tie-2 gene, which is known to be selectively expressed in endothelial cells. (1) how do you make a circle in minecraft commandWebBiological pathway information for HIF-2-alpha transcription factor network from Pathway Interaction Database. phone cases that chargehow do you make a christmas ornament wreath